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1

High-Energy Ball Milling as Green Process to Vitrify Tadalafil and Improve Bioavailability

Krupa, Anna, Descamps, Marc, Willart, Jean-Francois, Strach, Beata, Wyska, Elżbieta, Jachowicz, Renata, Danède, Florence

Journal:

Molecular Pharmaceutics

Year:

2016

Language:

english

File:

PDF, 5.25 MB

english, 2016

2

Solid state NMR and DSC methods for quantifying the amorphous content in solid dosage forms: an application to ball-milling of trehalose

R Lefort, A De Gusseme, J.-F Willart, F Danède, M Descamps

Journal:

International Journal of Pharmaceutics

Year:

2004

Language:

english

File:

PDF, 167 KB

english, 2004

3

On the polymorphism of griseofulvin: Identification of two additional polymorphs

Mahieu, Aurelien, Willart, Jean-francois, Dudognon, Emeline, Eddleston, Mark D., Jones, William, Danède, Florence, Descamps, Marc

Journal:

Journal of Pharmaceutical Sciences

Year:

2013

Language:

english

File:

PDF, 293 KB

english, 2013

4

A New Protocol To Determine the Solubility of Drugs into Polymer Matrixes

Mahieu, Aurélien, Willart, Jean-François, Dudognon, Emeline, Danède, Florence, Descamps, Marc

Journal:

Molecular Pharmaceutics

Year:

2013

Language:

english

File:

PDF, 1007 KB

english, 2013

5

High energy ball milling and supercritical carbon dioxide impregnation as co-processing methods to improve dissolution of tadalafil

Krupa, Anna, Descamps, Marc, Willart, Jean-François, Jachowicz, Renata, Danède, Florence

Journal:

European Journal of Pharmaceutical Sciences

Year:

2016

Language:

english

File:

PDF, 1.66 MB

english, 2016

6

Towards a better understanding of the different release phases from PLGA microparticles: Dexamethasone-loaded systems

Gasmi, H., Siepmann, F., Hamoudi, M.C., Danede, F., Verin, J., Willart, J. -F., Siepmann, J.

Journal:

International Journal of Pharmaceutics

Year:

2016

Language:

english

File:

PDF, 1.86 MB

english, 2016

7

PEO Hot Melt Extrudates for Controlled Drug Delivery: Importance of the Molecular Weight

Cantin, O., Siepmann, F., Danede, F., Willart, J.F., Karrout, Dr. Y., Siepmann, J.

Journal:

Journal of Drug Delivery Science and Technology

Year:

2016

Language:

english

File:

PDF, 1.18 MB

english, 2016

8

Trehalose or sucrose; which of the two should be used for stabilizing proteins in the solid state? A dilemma investigated by in-situ micro-Raman and dielectric relaxation spectroscopies during and after freeze-drying

Starciuc, Tatiana, Malfait, Benjamin, Danede, Florence, Paccou, Laurent, Guinet, Yannick, Correia, Natalia T., Hedoux, Alain

Journal:

Journal of Pharmaceutical Sciences

Year:

2019

Language:

english

File:

PDF, 1.43 MB

english, 2019

9

Mechanistic explanation of the (up to) 3 release phases of PLGA microparticles: Diprophylline dispersions

Tamani, F., Bassand, C., Hamoudi-Ben Yelles, M., Danede, F., Willart, J.F., Siepmann, F., Siepmann, J.

Journal:

International Journal of Pharmaceutics

Year:

2019

Language:

english

File:

PDF, 4.55 MB

english, 2019

10

PEO hot melt extrudates for controlled drug delivery: Importance of the type of drug and loading

Cantin, O., Siepmann, F., Willart, J.F., Danede, F., Siepmann, J., Karrout, Y.

Journal:

Journal of Drug Delivery Science and Technology

Year:

2020

File:

PDF, 21.82 MB

2020

11

First obtaining of glass solutions and phase diagram of glucose with fully tunable anomeric concentration

N. Dujardin, J.F. Willart, E. Dudognon, F. Danède, M. Descamps

Journal:

Journal of Pharmaceutical Sciences

Year:

2010

Language:

english

File:

PDF, 281 KB

english, 2010

12

Solid-state vitrification of crystalline griseofulvin by mechanical milling

Jean-François Willart, Laurent Carpentier, Florence Danède, Marc Descamps

Journal:

Journal of Pharmaceutical Sciences

Year:

2012

Language:

english

File:

PDF, 300 KB

english, 2012

13

A New Investigation of Rubidium Cadmium Trichloride

F. Hamzaoui, I. Noiret, G. Odou, F. Danede, F. Baert

Journal:

Journal of Solid State Chemistry

Year:

1996

Language:

english

File:

PDF, 251 KB

english, 1996

14

Rubidium Tetrachlorocadmate: X-Ray Diffraction Measurements and an Electronic Structure Study

I. Noiret, F. Baert, G. Odou, F. Danede, J. Schamps, P. Baranek

Journal:

Journal of Solid State Chemistry

Year:

1998

Language:

english

File:

PDF, 320 KB

english, 1998

15

Amorphization of sugar hydrates upon milling

J.F. Willart, N. Dujardin, E. Dudognon, F. Danède, M. Descamps

Journal:

Carbohydrate Research

Year:

2010

Language:

english

File:

PDF, 198 KB

english, 2010

16

Athermal character of the solid state amorphization of lactose induced by ball milling

J.F. Willart, V. Caron, R. Lefort, F. Danède, D. Prévost, M. Descamps

Journal:

Solid State Communications

Year:

2004

Language:

english

File:

PDF, 103 KB

english, 2004

17

Polymorphic transformation of the Γ-form of d-sorbitol upon milling: structural and nanostructural analyses

Jean-François Willart, Jacques Lefebvre, Florence Danède, Serge Comini, Philippe Looten, Marc Descamps

Journal:

Solid State Communications

Year:

2005

Language:

english

File:

PDF, 288 KB

english, 2005

18

Formation of lactose-mannitol molecular alloys by solid state vitrification

J.F. Willart, N. Descamps, V. Caron, F. Capet, F. Danède, M. Descamps

Journal:

Solid State Communications

Year:

2006

Language:

english

File:

PDF, 217 KB

english, 2006

19

The implication of the glass transition in the formation of trehalose/mannitol molecular alloys by ball milling

V. Caron, J.F. Willart, F. Danède, M. Descamps

Journal:

Solid State Communications

Year:

2007

Language:

english

File:

PDF, 412 KB

english, 2007

20

Direct crystal to glass transformation of trehalose induced by ball milling

J.F. Willart, A. De Gusseme, S. Hemon, G. Odou, F. Danede, M. Descamps

Journal:

Solid State Communications

Year:

2001

Language:

english

File:

PDF, 89 KB

english, 2001

21

Grinding of drugs with pharmaceutical excipients at cryogenic temperatures

T. P. Shakhtshneider, F. Danède, F. Capet, J. F. Willart, M. Descamps, S. A. Myz, E. V. Boldyreva, V. V. Boldyrev

Journal:

Journal of Thermal Analysis and Calorimetry

Year:

2007

Language:

english

File:

PDF, 265 KB

english, 2007

22

Grinding of drugs with pharmaceutical excipients at cryogenic temperatures

T. P. Shakhtshneider, F. Danède, F. Capet, J. F. Willart, M. Descamps, L. Paccou, E. V. Surov, E. V. Boldyreva, V. V. Boldyrev

Journal:

Journal of Thermal Analysis and Calorimetry

Year:

2007

Language:

english

File:

PDF, 232 KB

english, 2007

23

Evidence for a New Crystalline Phase of Racemic Ibuprofen

Emeline Dudognon, Florence Danède, Marc Descamps, Natália T. Correia

Journal:

Pharmaceutical Research

Year:

2008

Language:

english

File:

PDF, 202 KB

english, 2008

24

Influence of the growth method upon the phase transition of RbCdCl(mathsf{_{3}})

I. Noiret, J. Schamps, F. Danede, G. Odou, J. Lamiot

Journal:

The European Physical Journal B / Condensed Matter and Complex Systems

Year:

2004

Language:

english

File:

PDF, 612 KB

english, 2004

25

Characterization of the hidden glass transition of amorphous cyclomaltoheptaose

Nicolas Tabary, Aurélien Mahieu, Jean-François Willart, Emeline Dudognon, Florence Danède, Marc Descamps, Maryse Bacquet, Bernard Martel

Journal:

Carbohydrate Research

Year:

2011

Language:

english

File:

PDF, 785 KB

english, 2011

26

Solid state amorphization kinetic of alpha lactose upon mechanical milling

Vincent Caron, Jean-François Willart, Ronan Lefort, Patrick Derollez, Florence Danède, Marc Descamps

Journal:

Carbohydrate Research

Year:

2011

Language:

english

File:

PDF, 636 KB

english, 2011

27

Impact of the experimental conditions on drug release from parenteral depot systems: From negligible to significant

C. Delplace, F. Kreye, D. Klose, F. Danède, M. Descamps, J. Siepmann, F. Siepmann

Journal:

International Journal of Pharmaceutics

Year:

2012

Language:

english

File:

PDF, 1.48 MB

english, 2012

28

Comparison of physical and inhalation properties of spray-dried and micronized terbutaline sulphate

Thanh Huong Hoang Thi, Florence Danède, Marc Descamps, Marie-Pierre Flament

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2008

Language:

english

File:

PDF, 545 KB

english, 2008

29

Solid-Solid Transformation in Racemic Ibuprofen

Emeline Dudognon, Natália T. Correia, Florence Danède, Marc Descamps

Journal:

Pharmaceutical Research

Year:

2013

Language:

english

File:

PDF, 493 KB

english, 2013

30

Polymorphic transformation of anhydrous caffeine upon grinding and hydrostatic pressurizing analyzed by low-frequency raman spectroscopy

Hédoux, Alain, Guinet, Yannick, Paccou, Laurent, Danède, Florence, Derollez, Patrick

Journal:

Journal of Pharmaceutical Sciences

Year:

2013

Language:

english

File:

PDF, 440 KB

english, 2013

31

Structure determination of the crystalline phase of n -butanol by powder X-ray diffraction and study of intermolecular associations by Raman spectroscopy

Derollez, Patrick, Hédoux, Alain, Guinet, Yannick, Danède, Florence, Paccou, Laurent

Journal:

Acta Crystallographica Section B Structural Science

Year:

2013

Language:

english

File:

PDF, 1.16 MB

english, 2013

32

Mechanism of Solid State Amorphization of Glucose upon Milling

Dujardin, N., Willart, J. F., Dudognon, E., Danède, F., Descamps, M.

Journal:

Journal of Physical Chemistry B

Year:

2013

Language:

english

File:

PDF, 339 KB

english, 2013

33

Plastic and Glassy Crystal States of Caffeine

Descamps, Marc, Correia, Natália T., Derollez, Patrick, Danede, Florence, Capet, Frédéric

Journal:

Journal of Physical Chemistry B

Year:

2005

Language:

english

File:

PDF, 137 KB

english, 2005

34

Ice Particle Crystallization in the Presence of Ethanol: An In Situ Study by Raman and X-ray Diffraction

Facq, Sébastien, Danède, Florence, Chazallon, Bertrand

Journal:

Journal of Physical Chemistry A

Year:

2013

Language:

english

File:

PDF, 2.92 MB

english, 2013

35

Solid-state amorphization of linaprazan by mechanical milling and evidence of polymorphism

Willart, Jean-Francois, Durand, Morgan, Briggner, Lars-Erik, Marx, Anke, Danède, Florence, Descamps, Marc

Journal:

Journal of Pharmaceutical Sciences

Year:

2013

Language:

english

File:

PDF, 776 KB

english, 2013

36

PLGAs bearing carboxylated side chains: Novel matrix formers with improved properties for controlled drug delivery

Regnier-Delplace, C., Thillaye du Boullay, O., Siepmann, F., Martin-Vaca, B., Demonchaux, P., Jentzer, O., Danède, F., Descamps, M., Siepmann, J., Bourissou, D.

Journal:

Journal of Controlled Release

Year:

2013

Language:

english

File:

PDF, 1.82 MB

english, 2013

37

Detection of Two Glass Transitions on Triton X-100 under Confinement

Merino, Esther G., Neves, Paulo D., Fonseca, Isabel M., Danéde, Florence, Idrissi, Abdenacer, Dias, C. J., Dionísio, Madalena, Correia, Natália T.

Journal:

The Journal of Physical Chemistry C

Year:

2013

Language:

english

File:

PDF, 3.14 MB

english, 2013

38

Investigating the Influence of Morphology in the Dynamical Behavior of Semicrystalline Triton X-100: Insights in the Detection/Nondetection of the α′-Process

Merino, Esther G., Danéde, Florence, Derrollez, Patrick, Dias, Carlos J., Viciosa, M. Teresa, Correia, Natália T., Dionísio, Madalena

Journal:

Journal of Physical Chemistry B

Year:

2013

Language:

english

File:

PDF, 3.48 MB

english, 2013

39

Molecular Mobility of Amorphous S -Flurbiprofen: A Dielectric Relaxation Spectroscopy Approach

Rodrigues, A. C., Viciosa, M. T., Danède, F., Affouard, F., Correia, N. T.

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 2.55 MB

english, 2014

40

APPOINTMENTS NOT WITHIN THE COLONIAL SERVICE

Gue, E., Willart, J.F., Muschert, S., Danede, F., Delcourt, E., Descamps, M., Siepmann, J.

Journal:

Year:

1935

Language:

english

File:

PDF, 201 KB

english, 1935

41

Accelerated ketoprofen release from polymeric matrices: Importance of the homogeneity/heterogeneity of excipient distribution

Gue, E., Willart, J.F., Muschert, S., Danede, F., Delcourt, E., Descamps, M., Siepmann, J.

Journal:

International Journal of Pharmaceutics

Year:

2013

Language:

english

File:

PDF, 1.96 MB

english, 2013

42

Accelerated ketoprofen release from spray-dried polymeric particles: importance of phase transitions and excipient distribution

Gue, Emilie, Muschert, Susanne, Willart, Jean-Francois, Danede, Florence, Delcourt-Debruyne, Elisabeth, Descamps, Marc, Siepmann, Juergen

Journal:

Drug Development and Industrial Pharmacy

Year:

2015

Language:

english

File:

PDF, 2.98 MB

english, 2015

43

Metastability Release of the Form α of Trehalose by Isothermal Solid State Vitrification

Willart, J. F., Hédoux, A., Guinet, Y., Danède, F., Paccou, L., Capet, F., Descamps, M.

Journal:

Journal of Physical Chemistry B

Year:

2006

Language:

english

File:

PDF, 104 KB

english, 2006

44

A Stable Amorphous Statin: Solid-State NMR and Dielectric Studies on Dynamic Heterogeneity of Simvastatin

Nunes, Teresa G., Viciosa, M. Teresa, Correia, Natália T., Danède, F., Nunes, Rita G., Diogo, Hermínio P.

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 1.24 MB

english, 2014

45

Origin of the Dual Structural Transformation of Trehalose Dihydrate upon Dehydration

Willart, J. F., Danede, F., De Gusseme, A., Descamps, M., Neves, C.

Journal:

Journal of Physical Chemistry B

Year:

2003

Language:

english

File:

PDF, 123 KB

english, 2003

46

Long-range order in the high-temperature phase of

Leduc, F. X., Hedoux, A., Descamps, M., Danede, F., Odou, G.

Journal:

Physical Review B

Year:

1997

Language:

english

File:

PDF, 147 KB

english, 1997

47

Accelerated fenofibrate release from spray-dried microparticles based on polymer blends

Gué, E., Muschert, S., Willart, J.-F., Danède, F., Descamps, M., Delcourt-Debruyne, E., Siepmann, J.

Journal:

Journal of Drug Delivery Science and Technology

Year:

2014

Language:

english

File:

PDF, 709 KB

english, 2014

48

Metastable states in modulated phases of K 2 ZnCl 4 produced by crystal growth defects

Leduc, F.-X., Hedoux, A., Guinet, Y., Danede, F., Odou, G., More, M.

Journal:

Year:

1996

Language:

english

File:

PDF, 214 KB

english, 1996

49

Preparation of polymeric fenofibrate formulations with accelerated drug release: Solvent evaporation versus co-grinding

Jallouli, Y., Willart, J.-F., Siepmann, F., Descamps, M., Danede, F., Siepmann, J.

Journal:

Journal of Drug Delivery Science and Technology

Year:

2015

Language:

english

File:

PDF, 4.03 MB

english, 2015

50

Structure determination of the crystalline phase of n -butanol by powder X-ray diffraction and study of intermolecular associations by Raman spectroscopy

Derollez, Patrick, Hédoux, Alain, Guinet, Yannick, Danède, Florence, Paccou, Laurent

Journal:

Acta Crystallographica Section B Structural Science, Crystal Engineering and Materials

Year:

2013

Language:

english

File:

PDF, 1.19 MB

english, 2013

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